This is the fifth time the Bills are playing in prime-time this year and they are 3-1, though the loss did come in their only ...

Related: Where does Bills QB Josh Allen rank among NFL MVP contenders entering Week 13? What makes the team’s hot start to ...

Watch out for the tables on "Sunday Night Football." The nightcap of Sunday's action will be in northern New York with the ...

The Bills return from their bye week with a tough test on Sunday Night Football. Here's a look ahead to the matchup.

Simpson carried the ball 29 times against the Lions and set a new NFL record with 273 rushing yards, breaking his own record ...

It’s Week 13 in the NFL, and the Buffalo Bills are preparing to host the San Francisco 49ers on Sunday Night Football at 8:20 ...

The Buffalo Bills are on a fast track to win the AFC East championship and clinch a playoff spot. But that won't happen in ...

There is a High Risk of Weather Impact (ROWI) for the NFL's Sunday Night Football matchup between the San Francisco 49ers ...

The Buffalo Bills are heading out of the their bye and are set to face the San Francisco 49ers in Week 13 on “Sunday Night ...

There is a high Risk of Weather Impact (ROWI) for the NFL's Sunday Night Football matchup between the 49ers (5-6) and the ...

Before the season began, this week's game between the San Francisco 49ers and Buffalo Bills looked daunting. The 49ers were ...

Three teams face playoff-clinching scenarios in Week 13. Here's what the Bills, Lions and Chiefs need to earn a playoff berth ...